18 Comments
User's avatar
Neesha Shah's avatar

Fantastic info, Ox!

BowTied Gamblooor's avatar

Extremely well presented information, I have a bottle at home and will begin taking it.

yellow-smiley's avatar

what’s the differences between taking something like citrus bergamot vs. nattokinase?

BowTiedOx's avatar

They aren’t even in the same category… Nattokinase is a fibrinolytic, citrus bergamot affects cholesterol metabolism.

Matt Oliver's avatar

I have been using 8,000 FUs for about a month and have noticed slight decreases in BP from baseline. Isn’t there some hematocrit lowering effects from this supplement as well?

BowTiedOx's avatar

Potentially but nothing published

Coggystyle's avatar

Great post, but Double Wood latest COA on numerous products are bad. Wouldn’t use them currently.

BowTiedOx's avatar

Looked into is, seeing nothing other than some older reports (they have been bought buy another firm) & their COA & testing for nattokinase passed (actually more per serving by a few fu than advertised) + FDA approved GMP certified facility

I’m not loyal or attached to them in anyway, like I said, I prefer doctors now or PE, but not enough evidence to change my recommendations/I’ll still use their products.

That said, I do appreciate you bringing this up & if I find anything damning will correct & comp your subscription for bringing it to my attention.

Coggystyle's avatar

I got your back, dude!

BowTShrike's avatar

Great post! This one, along with streptokinase and staphylokinase, not being real kinases drives me nuts.

I wonder if this is something that your body adapts to, similar to aspirin. American Heart dropped daily baby aspirin from its recommendations because your body adapts to it after about a year. If I were designing a research study, I would compare cycling vs continuous.

To add more context on viruses and clotting... clotting is one of the defense mechanisms in the blood for stopping viruses (not just the one everyone now knows) and other pathogens. So some clotting is good... but too much clotting (or failing to remove the clots) kills. Your body has more layers of defense than a competent lawyer or nuclear power plant, so blocking one may not have a meaningful impact on many infections, especially in an immunocompetent adult. And if you have bigger problems (ie higher risk of clots), prioritizing minimizing the thing that can kill you is smart.

I'd also note that tPA and other fibrinolytics also help cancer cells move around. Personally, I would be careful if I had a tumor.

Kieran's avatar

Great clear article! If taking Xarelto (rivaroxaban) to thin blood due to clots which required hospitalisation last summer, is it not recommended to take this? From what I can find, Xarelto is an antithrombotic drug which that 1 study warned may cause issues while taking Nattokinase

BowTiedOx's avatar

Like I said, this is an example where you need to discuss it with whoever is prescribing you that drug, I am not in a position to know your health status nor am I qualified to give that advice

Nomadic Nomad's avatar

Any difference in taking it on empty stomach vs with food?

Thank you!

BowTiedOx's avatar

Never noticed a difference

Nomadic Nomad's avatar

Got it, thank you. I wasn't sure if there are any absorption differences or whatnot.

Jayhawk Man's avatar

Read I think from Grimhood (?) on X that taking it on an empty stomach in the AM is best for absorption. Would need to double check that though. I take 4 in the AM pre-breakfast (8,000 IUs).

Nomadic Nomad's avatar

Solid copy. This is what I do too, just easier this way. But I take 12k IUs.

OPF's avatar

Been taking 8.000 fu for 5 days now. Been having more regular morning woods

+ Stronger erections

In combination with some lifestyle changes and more cardio in the past months.

Will continue taking this, game changer!